Research Articles
DCAF5: The Cellular Quality Controller Turned Cancer Biomarker
Discover how DCAF5 serves as both a promising cancer biomarker and potential therapeutic target through comprehensive pan-cancer analysis and functional studies.
The Hidden Language of RNA: How Tiny Chemical Tags Are Revolutionizing Colorectal Cancer Treatment
Exploring how RNA methylation modifications influence colorectal cancer prognosis and immunotherapy response through dynamic epigenetic regulation.
Disarming Cancer's Shield: How a Cellular "Saboteur" Helps Tumors Hide
Discover how the ATXN3 protein regulates PD-L1 in cancer cells and enables tumor immune evasion through CRISPR screening research.
The Invisible Shield: How Cancer Hides from Our Immune System
Discover how cancer evades immune detection through MHC-I pathway manipulation and the breakthrough discovery of a membrane-associated inhibitory axis.
Attacking the Attackers: How a Cellular "Janitor" Helps Cancer Hide
New research reveals how USP24 stabilizes PD-1 protein in T cells, helping cancer evade immune detection and suggesting new therapeutic approaches.
Unleashing the Army Within: How a New Pill Could Revolutionize Cancer Fight
Discover how a new oral Cbl-b inhibitor pill could revolutionize cancer treatment by supercharging the body's immune system to fight tumors effectively.
Unlocking the Immune System: How a Revolutionary Cancer Drug Fights Leukemia on Two Fronts
Discover how DS-5272 inhibits MLL-fusion leukemia through dual mechanisms: direct p53 activation and immune system engagement.
Mitochondrial Sabotage: How Cancer Cells Disarm Immune Defenses and New Hope for KRAS-Mutant Cancers
Discover how KRAS-mutant cancers use mitochondrial transfer to evade immune attacks and new therapeutic strategies to counter this biological warfare.
The Double Agent in Our Blood: Turning Cancer's Greatest Ally into its Worst Enemy
Discover how a new molecular glue therapy targets regulatory T-cells to enhance cancer immunotherapy effectiveness.
The Double-Agent in Our Cells: How TRIM7 and RACO-1 Team Up to Thwart Cancer Immunotherapy
Discover how TRIM7 and RACO-1 proteins collaborate to create resistance to cancer immunotherapy, making tumors invisible to immune detection.